Bioavailability - the key indicator of health supplement efficacy.

March 12, 2022

Key factors influencing the effectiveness of health supplements.

One of the key indicators of supplements nutrition is bioavailability. It is the administered dose fraction/percentage that your body can absorb and utilize. In other words, it is a measure of how effectively your body can use the nutrient contained in the preparation. So if you use supplements and want them to actually work, bioavailability is key.

Nutritional supplements with higher bioavailability are way more effective, as they help your body to absorb more of the active substance, without having to take high doses.

Bioavailability of the supplements and drugs is highly dependent on on the properties of the form in which they are administered.

Dietary supplements and drugs administered orally, active substances that are poorly soluble in water, as well as ingredients requiring longer absorption time, usually show low bioavailability.

Most of the orally administered nutrient is metabolized and eliminated before even reaching blood circulation. Only about ten percent of the active substances in vitamins and minerals in traditional tablets or capsules are absorbed by the body! On the other hand many nutrients are extremely sparingly soluble in water, which is why they are often not absorbed at a satisfactory level. Some of them need fat for this, which makes it even more difficult for the body to absorb them. Insufficient time that the active substance spends in the gastrointestinal tract is also a common cause of low bioavailability.

The solution for the above issues is the micellation - a unique method whereby fat-soluble vitamins and vital substances become water-soluble.

Since the human body consists of around 60-70% of water, this is where the transport of nutrients is based. Blood, which performs transport functions, also consists of nearly 90% water, therefore substances that are distributed by water must dissolve well in it.

Polymeric micelles, small size (10-100nm) hudrophilic shell is an excellent carrier for active substances. They show high stability and prolonged circulation time in the blood. Micellised products have been shown to be an excellent carrier of hydrophobic substances. Therefore, this solution is particularly important for all vitamins and other fat-soluble substances. These include vitamins A, D, E, K, beta-carotene, as well as Coenzyme Q10 and Omega-3 fatty acids. On top of the above the micelles have a high thermal, mechanical, sensory and microbiological stability. As a result, the nutrients in the body also get to where they are needed.

Micellation is a natural method that does not require the addition of synthetic ingredients like stabilisers, anti caking agents and flavour enhancers. The absorption of active substances, which amounts to about 3 to 5% with commercially available preparations, with micellation, can be increased to an efficiency of almost 100%. On top of the above the micelles have a high thermal, mechanical, sensory and microbiological stability. As a result, the nutrients in the body also get to where they are needed. They even survive the acidic environment of the stomach unscathed.

Check out the BIOCANNOVEA First micellised health supplements in Ireland - absolute novelty on the health supplements market.